A happy-go-lucky Mumbai suburban housewife Sulochana, fondly known as Sulu, lands the role of a night RJ, resulting in drastic changes to her routine life.

Vidya (Moushumi Chatterjee) and Raja (Raju Shrestha) live in poverty. They get separated due to certain circumstances. Vidya starts working at Anand's (Jeetendra) house as a maid. Raja is forced to beg for a local gang. While Vidya is attending to her chores, the alcoholic, Anand, tries to molest her. She escapes but is unfortunately hit by a speeding vehicle driven by Sunil Verma (Navin Nischol). This accident makes her visually impaired. The guilt-ridden Anand wants to apologize to Vidya. Will she accept the apology? Will Vidya reunite with her brother?

In 1985, Star Trek's George Takei joined a group of dedicated fans to make a student film deep in the California forest—only for the footage to mysteriously vanish. Nearly 40 years later, Beam Me Up, Sulu unearths this lost film, revealing not just a piece of fan history but a broader story of representation, resilience, and the ongoing fight for inclusion in media and society.

All goes well for a group of friends and their respective romantic partners when they fall in love. However, things start taking a dark turn when love gives way to deceit and revenge.